Dental implants are often made of titanium alloys. Implant therapy currently promises a good long-term result without impacting health; however, its success depends on many factors. In this article, the authors focus on the most common risk factors associated with metallic surgical implants.
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This review is based on current titanium research demonstrating the many factors that can pose a negative impact on human health when exposed to the various forms of titanium, including its relationship and interactions with other metals.
Cell viability is negatively correlated with titanium concentration. Further, titanium debris might lead to an inflammatory biologic response of dental peri-implant tissue.
Titanium particles/ions detected in peri-implant tissues have been considered as a potential etiologic factor for crestal bone loss around oral implants. However, the definite impact of titanium wear particles on the health of surrounding structures remains undetermined.
Epigenetic changes are associated with various inflammatory diseases and are influenced by environmental factors. Recent data support an association between titanium dissolution products and peri-implantitis.
Degenerative changes were reported in macrophages and neutrophils that phagocytosed titanium microparticles, and mutations occurred in human cells cultured in medium containing titanium-based nanoparticles.
Michael Foley, founder of Emerginnova, was honored to have the opportunity to fly to Cincinnati Ohio to meet with one of the leading inventors, developers and founders of modern dental implant surgery, Dr. Jack Hahn.
Corrosion of titanium dental implants has been associated with implant failure and is considered one of the triggering factors for peri-implantitis. Corrosion of dental implants is concerning, because a large amount of metal ions and debris are generated in this process, of which accumulation may lead to adverse tissue reactions in the oral environment.