Zeramex Company Blog

Intracellular uptake and toxicity of three different Titanium particles

Intracellular uptake and toxicity of three different Titanium particles

Nickel in the alloy NiTi induced an increase in the toxic potential compared to Titanium microparticles.

Titanium is a highly thrombogenic biomaterial: possible implications for osteogenesis

This study indicates that titanium is unsuitable as a biomaterial in devices which are in direct contact with blood for a prolonged period.

The Biological Effect of Particulate Titanium Contaminants of Dental Implants on Human Osteoblasts and Gingival Fibroblasts

The Biological Effect of Particulate Titanium Contaminants of Dental Implants on Human Osteoblasts and Gingival Fibroblasts

Cell viability is negatively correlated with titanium concentration. Further, titanium debris might lead to an inflammatory biologic response of dental peri-implant tissue.

Titanium as a modifier of the peri-implant microbiome structure

Titanium as a modifier of the peri-implant microbiome structure

Recent data support the implication of accelerated titanium dissolution products in peri-implantitis. It is unknown whether these dissolution products have an effect on the peri-implant microbiome, the target of existing peri-implantitis therapies.

Cytokine pathways in the implant area during osseointegration from TNF-α to RANTES/CCL5 overexpression with longterm, negative immune response, and effects

Ischaemic hypoxic medullary bone occurs when there is a disruption in the vascular supply of that bone tissue. Such disruption can occur when a thrombus (clot) is formed and does not subsequently break down (fibrinolysis).

Titanium particles in tissues from peri-implant mucositis: An exfoliative cytology-based pilot study

Titanium particles in tissues from peri-implant mucositis

To evaluate the presence of titanium particles in the peri-implant mucosa of unloaded single implants.

Titanium implants and silent inflammation in jawbone—a critical interplay of dissolved titanium particles and cytokines TNF-α and RANTES/CCL5 on overall health?

All DTI (Dental Titanium Implant)-FDOJ (Fatty Degeneration with Osteonecrosis of the Jaw) samples showed RANTES/CCL5 (R/C) as the only extremely overexpressed cytokine. DTI-FDOJ cohort showed a 30-fold mean overexpression of R/C as compared with a control cohort of 19 healthy JB samples.

Macrophage polarization in aseptic bone resorption around dental implants induced by Ti particles in a murine model

Macrophage polarization in aseptic bone resorption around dental implants induced by Ti particles in a murine model.

Titanium particles/ions detected in peri-implant tissues have been considered as a potential etiologic factor for crestal bone loss around oral implants. However, the definite impact of titanium wear particles on the health of surrounding structures remains undetermined.

Pathogenesis of peri-implantitis

Peri-implantitis is a pathogenetically complex clinical picture and, in addition to local effects, has systemic effects depending on individual genetic susceptibility. It has some similarities to periodontitis but differs in the taxonomic biofilm composition and is also involved in foreign body reactions to the implant material.

Metal Nanoparticles Released from Dental Implant Surfaces: Potential Contribution to Chronic Inflammation and Peri-Implant Bone Loss

Metal Nanoparticles Released from Dental Implant

The aim of this study is to identify the role of titanium nanoparticles released form the implants on the chronic inflammation and bone lysis in the surrounding tissue.

Implant Tribune

Spotlight on ZERAMEX®XT for the month of April 2020